[177Lu-DOTA0,Tyr3]octreotate for somatostatin receptor-targeted radionuclide therapy
نویسندگان
چکیده
منابع مشابه
Targeted Radionuclide Therapy with A 177Lu-labeled Anti-HER2 Nanobody
RIT has become an attractive strategy in cancer treatment, but still faces important drawbacks due to poor tumor penetration and undesirable pharmacokinetics of the targeting vehicles. Smaller radiolabeled antibody fragments and peptides feature highly specific target accumulation, resulting in low accumulation in healthy tissue, except for the kidneys. Nanobodies are the smallest (MW<15 kDa) f...
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متن کاملDeadtime effects in quantification of 177Lu activity for radionuclide therapy
BACKGROUND The aim of this study was to investigate the deadtime (DT) effects that are present in 177Lu images acquired after radionuclide therapy injection, assess differences in DT based on the full spectrum and the photopeak-only measurements, and design a method to correct for the deadtime losses. A Siemens SymbiaT SPECT/CT camera with a medium energy collimator was used. A 295-mL bottle wa...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2001
ISSN: 0020-7136,1097-0215
DOI: 10.1002/1097-0215(20010601)92:5<628::aid-ijc1244>3.0.co;2-l